Bioinformatics Research Scientist

US-TN-Memphis
Job ID
36832
Department
Developmental Neurobiology
Category
Bioinformatics

Summary

St. Jude Children’s Research Hospital’s Department of Developmental Neurobiology is looking for a highly motivated bioinformatics research scientist as the key analyst for the epigenomics and single cell sequencing projects of the Department of Developmental Neurobiology, in close collaboration with the Department of Computational Biology. The goal of the Developmental Neurobiology Department, led by Dr. Michael Dyer, an HHMI investigator, is to understand how neurons are formed during development and how that process can become deregulated in pediatric brain tumors.  Emphasis is placed on applying cutting edge computational approaches to some of the most innovative biological studies in the field. Members of the Department of Developmental Neurobiology publish in high profile journals including Nature, Cell, Science, Cancer Cell, Neuron, Nature Neuroscience, Nature Genetics, Cell Stem Cell and many others. The Computational Biology Department has a well-established track record in leading bioinformatics analysis for high-profile genomic and translational research projects such as the St. Jude/Washington University Pediatric Cancer Genome Project. Specific projects include the integrative analysis of ChIP-seq of histone marks and transcription factors, ATAC-seq, Hi-C, Capture-seq, whole-genome and whole exome sequencing, whole transcriptome RNA-seq data to understand the mechanism of key molecular pathways involved in tumorigenesis especially pediatric brain and solid tumors. Candidates with an understanding of epigenomics, clonal analysis and single cell RNA sequencing analysis and with strong problem solving skills, attention to detail, critical thinking, and expertise in next-generation sequencing data analysis are highly encouraged to apply for this position.

Responsibilities

 

 

Minimum Education

  • Ph.D. in Molecular Biology, Biochemistry, Computer Science, Statistics, Mathematics, Bioinformatics or related field required
  • Ph.D. which must include research related to bioinformatics (such as analysis of sequence data, microarrays, SNPs, image data, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software). 
    OR
  • If Ph.D. with no bioinformatics research, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required

Minimum Experience

  • Ph.D which must include research related to bioinformatics (such as analysis of sequence data, microarrays, SNPs, image data, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software); OR If Ph.D with no bioinformatics research, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required
  • Experience with programming languages such as Perl, C, or Java required

Preferred Skills

 

  • Experience with Python and knowledge on statistical analysis package such as R and Matlab is highly desired. Experience in epigenetics analysis such as ChIP-seq, ATAC-seq, HiC, WGBS, RNA-seq, single cell sequencing is preferred. Knowledge about neurobiology is also a plus.

EEO

St. Jude is an Equal Opportunity Employer

No Search Firms:

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Options

Sorry the Share function is not working properly at this moment. Please refresh the page and try again later.
Share on your newsfeed

Stay connected

Not ready to apply? Become a St. Jude Career Insider to stay up-to-date on our opportunities.