St. Jude Children’s Research Hospital, a premier center for biomedical investigation located in Memphis, Tennessee, USA, is expanding its program in proteomics, metabolomics, and mass spectrometry. The hospital is seeking individuals to help lead this effort that will interface with the many world-class research programs within the institution.
The Proteomics and Mass Spectrometry core provides both clinical and research investigators at St. Jude Children’s Research Hospital with state of the art Mass Spectrometers for protein analysis. Services provided by the laboratory include gel electrophoresis for protein expression analysis, protein identification, intact mass measurement of proteins and peptides, analysis of post-translational modifications as well as quantitative proteomics. Services also include initial consultation in experimental design, sample processing, acquisition of raw data and data analysis. Expertise is available in the laboratory and in the Bioinformatics group to assist with data analysis and interpretation. Since 2002 the laboratory has supported nearly 100 principal investigators in 25 departments and contributed to more than 100 publications. The proteomics core consists of 7 mass spectrometers including an Orbitrap Fusion, 3 Q-Exactive HFs, two Orbitrap Elites, and a Waters LCT.
The Proteomics Scientist in the Proteomics core takes a lead role in project consultation, experimental design, data collection, data analysis, data visualization, and statistical analysis. Provides help with sample prep, instrumentation, and software used in the proteomics core. Interacts with bioinformatics group to improve and develop new software tools. May act as project manager of designated research project and/or technology development. Provides project oversight, scientific advice, support, or other necessary input to achieve established objectives. Develops independent proteomics/metabolomics projects. Ensures that efficient and prompt help is provided to the SJCRH investigators.
Ten (10) years of laboratory research experience in the field of proteomics, metabolomics, or mass spectrometry required with a master’s degree. Six (6) years of laboratory research experience in the field proteomics, metabolomics, or mass spectrometry required with a Ph.D.
Postdoctoral experience is preferred.
Proven track record of peer reviewed publications is preferred.
Hands on experience with mass spectrometers is required.
Experience with large-scale data analysis preferred. Experience with pathway analysis, statistical analysis is helpful.